Programme Outline

DAY 1, DECEMBER 8, MONDAY: Balmoral Suite, De Vere Beaumont Estate
12:00-13:00Registration for Day 1 Participants
13:00-15:30 Advanced monitoring in the neuroICU: scientific background, goals and methods
..and not just about spreading depolarisations
Understanding clinical pathophysiology through multimodal monitoring (exact title TBC)
Professor Raimund Helbok: Chairman of Neurology, Keplerklinikum Linz
Pathophysiology first: technology second
Understanding clinical pathophysiology through metabolic imaging
Professor Jonathan Coles, Intensive Care Medicine, University of Cambridge
Metabolic dysfunction is complex and spatially heterogeneous
Spreading depolarisations in multimodal datastreams in the neuroICU: perhaps we CAN and should start to manage SDs in the neuroICU?
Professor Jed Hartings, Department of Neurosurgery, University of Cincinnati
Why we need to think about managing SDs
15:30-16:00Tea break
16:00-17:30Demonstration Seminar
Dick Moberg, Moberg Analytics and his team: Prof Jed Hartings, University of Cincinnati
Learn something of integrating specialist datafeeds - such as ECoG or other electrophysiology or chemistry with the more regular channels that ICM+ samples - into a single high resolution dataset accessible to evolving analytical software and AI. One practical example will show that it is becoming easier to detect and assess SDs automatically. (Details TBC).
19:30-22:00Welcome Canapé Reception for Days 2-4 Participants: Balmoral Suite
DAY 2, DECEMBER 9, TUESDAY Balmoral Suite: Parallel sessions
8:00-9:00Registration
Main Session: Room A+B
9:00-18:00Aspects of spreading depolarisations with clinical relevance
Free papers and posters
Invited discussant
Prof Jonathan Coles, Intensive Care Medicine, University of Cambridge
Keynote speakers
Designing an escalation clinical trial to address complex pathophysiology in severe TBI/ABI (INDICT)
Prof Jed Hartings, Neurosurgery, University of Cincinnati
The impact of circadian and sleep disruption on CSD susceptibility
Dr Philip Holland, King’s College London Headache Group Lead
Chemistry-directed management of traumatic brain injury
Prof Peter Hutchinson, Neurosurgery, University of Cambridge
Parallel Session: Small Syndicate Room 1
9:00-16:00ICM+ Course
Prof Peter Smielewski & Team, Department of Neurosurgery, University of Cambridge
19:00-22:00Conference Dinner, De Vere Estate: Chapel Dining Hall
DAY 3, DECEMBER 10, WEDNESDAY Balmoral Suite
9:00-12:30Basic neuroscience: SD, metabolism and epileptology topics
Free papers and posters
Keynote speaker
Interactions of spreading depolarisations and seizures
Prof John Jefferys, Universities of Oxford and Prague
12:30-13:30Lunch
13:00-19:00Excursion / Free time
19:00-22:00Buffet Supper: De Vere Beaumont Restaurant
DAY 4, DECEMBER 11, THURSDAY Balmoral Suite
9:00-15:50Basic neuroscience: SD, metabolism and epileptology topics
Free papers and posters
Keynote speaker
Neuron-glia metabolic coupling: a cornerstone of brain homeostasis with implications for physiopathological mechanisms of brain diseases
Prof Pierre Magistretti, King Abdullah University of Science and Technology
15:50-Sharon Jewell to summarise and close meeting, present best poster and best oral presentation award, and announce next meeting.